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Indication
Ibuprofen contains the active ingredient ibuprofen, which belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).
It works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of various chemicals in the body, some of which are known as prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause pain, swelling and inflammation. Ibuprofen is therefore used to relieve pain and inflammation.
All the medicines in this group (NSAIDs) reduce inflammation caused by the body's own immune system, and are effective pain killers. Ibuprofen can be used to relieve pain such as muscular aches and pains, period pains, headache, backache, rheumatic pain, dental pain and neuralgia. It can also reduce feverishness and the symptoms of colds and flu.

Special precautions
If symptoms persist despite treatment, seek medical advice from your doctor or pharmacist.
Some brands or preparations of medicine containing this active ingredient are not recommended for use in children under certain ages. Consult the package literature provided with the medicine for further information.
People with impaired kidney, liver or heart function who are taking Ibuprofen should have their kidney function monitored.
Use with caution in:

1. Asthma
2. Bleeding disorders
3. Decreased heart function
4. Decreased kidney function
5. Decreased liver function
6. Elderly people
7. High blood pressure (hypertension)
8. History of allergies
9. History of diseases of the stomach or intestines
   Not to be used in
   Allergy to aspirin or other medicines in this class (NSAIDs)
   History of narrowing of the airways (bronchospasm), inflammation of the nasal membrane (rhinitis) or itchy rash (urticaria) caused by aspirin or other NSAIDs
   Peptic ulcer or a history of this
   This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
   If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

   Label warnings
   Take this medication with or after food.

Order and buy Ibuprofen only with reliable pharmacy providers!

Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with Ibuprofen. Because a side effect is stated here, it does not mean that all people using Ibuprofen will experience that or any side effect.
Headache
Rash
Blood disorders
Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain
Indigestion (dyspepsia)
Retention of water in the body tissues (fluid retention)
Dizziness
Damage to the kidneys
Death of the outer layer of the skin (epidermal necrolysis)
Bleeding from the stomach or intestine
Liver disorders
Allergic reactions such as skin rash, swelling of the lips, tongue and throat (angioedema) or narrowing of the airways (bronchospasm)
Stomach or duodenal ulcer
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

Drug Interactions
Ibuprofen may prevent the removal of lithium and methotrexate from the body, resulting in increased blood levels of these medicines.
There may be an increased risk of bleeding from the gut if Ibuprofen is taken with blood thinning or anti-clotting medicines such as warfarin.
There may be an increased risk of Ibuprofen side effects such as stomach irritation if Ibuprofen is taken with corticosteroids such as prednisolone.
Ibuprofen may decrease the blood pressure lowering effects of amlodipine and possibly other antihypertensive medicines.
The use of Ibuprofen with diuretics, ACE inhibitors or ciclosporin may increase the risk of kidney problems.
NSAIDs should not be used within 8-12 days of taking mifepristone.
Ibuprofen should not be taken with any other NSAID, due to an increased risk of side effects of Ibuprofen.

Disclaimer
Always read informational leaflet before using medicine! The information can be changed and completed!!